Article: Intrinsic membrane plasticity via increased persistent sodium conductance of cholinergic neurons in the rat laterodorsal tegmental nucleus contributes to cocaine-induced addictive behavior.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Kamii H; Kurosawa R; Taoka N; Shinohara F; Minami M; Kaneda K Eur. J. Neurosci., 2015
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Other | laterodorsal tegmental nucleus burst-firing cholinergic neuron | cell capacitance (pF) | 24.1 ± 1.7 (27) | 24.1 (pF) | Data Table |
Other | laterodorsal tegmental nucleus regular-firing cholinergic neuron | cell capacitance (pF) | 22.3 ± 1.1 (65) | 22.3 (pF) | Data Table |
Other | laterodorsal tegmental nucleus regular-firing cholinergic neuron | fast AHP amplitude (mV) | 12.7 ± 0.9 (65) | 12.7 (mV) | Data Table |
Other | laterodorsal tegmental nucleus burst-firing cholinergic neuron | input resistance (MΩ) | 258.1 ± 11.3 (27) | 258.1 (MΩ) | Data Table |
Other | laterodorsal tegmental nucleus regular-firing cholinergic neuron | input resistance (MΩ) | 231.0 ± 5.9 (65) | 231.0 (MΩ) | Data Table |
Other | laterodorsal tegmental nucleus regular-firing cholinergic neuron | medium AHP amplitude (mV) | 21.5 ± 0.8 (65) | 21.5 (mV) | Data Table |
Other | laterodorsal tegmental nucleus regular-firing cholinergic neuron | resting membrane potential (mV) | -71.4 ± 0.6 (41) | -71.4 (mV) | Data Table |
Other | laterodorsal tegmental nucleus burst-firing cholinergic neuron | resting membrane potential (mV) | -71.7 ± 1.2 (18) | -71.7 (mV) | Data Table |
Other | laterodorsal tegmental nucleus regular-firing cholinergic neuron | spike amplitude (mV) | 64.2 ± 1.0 (65) | 64.2 (mV) | Data Table |
Other | laterodorsal tegmental nucleus burst-firing cholinergic neuron | spike amplitude (mV) | 66.5 ± 1.7 (27) | 66.5 (mV) | Data Table |
Other | laterodorsal tegmental nucleus burst-firing cholinergic neuron | spike threshold (mV) | -48.1 ± 0.9 (27) | -48.1 (mV) | Data Table |
Other | laterodorsal tegmental nucleus regular-firing cholinergic neuron | spike threshold (mV) | -47.3 ± 0.8 (65) | -47.3 (mV) | Data Table |
Other | laterodorsal tegmental nucleus regular-firing cholinergic neuron | spontaneous firing rate (Hz) | 1.4 ± 0.2 (24) | 1.4 (Hz) | Data Table |
Other | laterodorsal tegmental nucleus burst-firing cholinergic neuron | spontaneous firing rate (Hz) | 1.4 ± 0.2 (9) | 1.4 (Hz) | Data Table |
Metadata values
Experimental condition | Value |
---|---|
Species | Rats |
ElectrodeType | Patch-clamp |
Strain | Rats, Sprague-Dawley |
JxnPotential | Corrected |
InternalSolution | 5.0 |
ExternalSolution | 5.0 |
PrepType | in vitro |
AnimalAge | 14.0 - 35.0 |
RecTemp | 33.0 - 34.0 |
JxnOffset | -10.0 |
internal_0_pH | 7.3 |
internal_0_Mg | 2.0 |
internal_0_Na | 4.9 |
internal_0_K | 160.0 |
internal_0_GTP | 0.3 |
internal_0_ATP | 2.0 |
internal_0_EGTA | 0.2 |
internal_0_HEPES | 10.0 |
internal_0_Cl | 14.0 |
external_0_pH | 7.4 |
external_0_Mg | 1.0 |
external_0_Na | 152.25 |
external_0_K | 2.5 |
external_0_Cl | 133.5 |
external_0_Ca | 2.0 |
external_0_glucose | 25.0 |
Data table listing
Data Table | Article Title | Authors | Journal | Year | Table needs expert? | Ephys table mentions | Curated by | Times validated |
---|---|---|---|---|---|---|---|---|
45479 | Intrinsic membrane plasticity via increased persistent sodium conductance of cholinergic neurons in the rat laterodorsal tegmental nucleus contributes to cocaine-induced addictive behavior. | Kamii H; Kurosawa R; Taoka N; Shinohara F; Minami M; Kaneda K | Eur. J. Neurosci. | 2015 | False | 8 | Shreejoy Tripathy, James liu, | 1 |